Dorin-Bogdan Borza Selected Research

Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome)

1/2021	Laminin-521 is a Novel Target of Autoantibodies Associated with Lung Hemorrhage in Anti-GBM Disease.
9/2015	A case of subepidermal blistering disease with autoantibodies to multiple laminin subunits who developed later autoantibodies to alpha-5 chain of type IV collagen associated with membranous glomerulonephropathy.
10/2008	Antigenic heterogeneity of IgA anti-GBM disease: new renal targets of IgA autoantibodies.
4/2007	The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain.
1/2007	Autoepitopes and alloepitopes of type IV collagen: role in the molecular pathogenesis of anti-GBM antibody glomerulonephritis.
12/2005	Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen.
2/2005	Recurrent Goodpasture's disease secondary to a monoclonal IgA1-kappa antibody autoreactive with the alpha1/alpha2 chains of type IV collagen.
10/2003	A human-mouse chimera of the alpha3alpha4alpha5(IV) collagen protomer rescues the renal phenotype in Col4a3-/- Alport mice.

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Dorin-Bogdan Borza Research Topics

Disease

13	Glomerulonephritis 02/2013 - 05/2003
11	Hereditary Nephritis (Alport Syndrome) 02/2021 - 10/2002
9	Nephritis 05/2013 - 05/2002
8	Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome) 01/2021 - 10/2003
7	Proteinuria 02/2021 - 10/2008
6	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2021 - 04/2012
5	Albuminuria 01/2018 - 12/2009
4	Hemorrhage 01/2021 - 11/2003
4	Kidney Diseases (Kidney Disease) 01/2018 - 02/2013
3	Lupus Nephritis 07/2019 - 10/2008
3	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2016 - 04/2012
3	Chronic Kidney Failure (Chronic Renal Failure) 04/2012 - 05/2003
2	Autoimmune Diseases (Autoimmune Disease) 09/2010 - 10/2003
2	Renal Insufficiency (Renal Failure) 12/2008 - 07/2006
1	Hemoptysis 01/2021
1	Lung Injury 01/2021
1	Skin Diseases (Skin Disease) 09/2015
1	Bullous Pemphigoid (Pemphigoid) 09/2015
1	Chronic Renal Insufficiency 01/2015
1	Microscopic Polyangiitis 09/2012
1	Hypersensitivity (Allergy) 09/2012
1	Segmental glomerulosclerosis 01/2011
1	Inflammation (Inflammations) 09/2010
1	Necrosis 12/2009
1	Hematuria 10/2008
1	Hypoxia (Hypoxemia) 04/2007
1	Neoplasms (Cancer) 07/2006
1	Rapidly progressive glomerulonephritis with pulmonary hemorrhage 05/2003

Drug/Important Bio-Agent (IBA)

19	CollagenIBA 01/2021 - 10/2002
11	antiglomerular basement membrane antibodyIBA 01/2021 - 05/2002
11	AutoantibodiesIBA 01/2021 - 11/2003
10	AntibodiesIBA 01/2018 - 05/2003
8	Immunoglobulin G (IgG)IBA 01/2021 - 10/2008
8	IsoantibodiesIBA 05/2013 - 05/2003
6	AntigensIBA 05/2014 - 05/2003
5	Collagen Type IV (Type IV Collagen)IBA 02/2021 - 05/2003
5	EpitopesIBA 01/2021 - 01/2007
5	Antigen-Antibody Complex (Immune Complex)IBA 01/2018 - 01/2011
3	CreatinineIBA 02/2021 - 10/2008
3	AutoantigensIBA 01/2021 - 07/2010
3	Complement Membrane Attack Complex (Membrane Attack Complex)IBA 01/2018 - 01/2013
3	Complement System Proteins (Complement)IBA 01/2018 - 01/2013
2	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 09/2012 - 01/2007
2	Messenger RNA (mRNA)IBA 12/2009 - 04/2007
2	Immunoglobulin A (IgA)IBA 10/2008 - 02/2005
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 02/2021
1	Urea (Carbamide)FDA LinkGeneric 02/2021
1	FumaratesIBA 01/2021
1	PeroxidasinIBA 07/2019
1	Complement Factor B (Factor B)IBA 01/2018
1	LectinsIBA 01/2018
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2017
1	Laminin (Merosin)IBA 09/2015
1	OligonucleotidesIBA 01/2015
1	Bovine Serum AlbuminIBA 01/2013
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 09/2012
1	Peroxidase (Myeloperoxidase)IBA 09/2012
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 09/2010
1	OvalbuminIBA 12/2009
1	NitratesIBA 12/2009
1	Fibronectins (Fibronectin)IBA 05/2008
1	Betamethasone (Celestone)FDA Link 05/2008
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2007
1	Integrin alphaVbeta3IBA 07/2006
1	Protein Isoforms (Isoforms)IBA 12/2005
1	anti-glomerular basement membrane autoantibodyIBA 05/2003

Therapy/Procedure

4	Therapeutics 01/2018 - 03/2009
3	Kidney Transplantation 07/2010 - 05/2003
1	Transplantation 07/2010